I mean, think about it. A lot of the transformations in the series resemble henshin sequences.
There are enough human characters to balance out with the robot characters (in fact, most of the robots are human in some form).
And it wouldn't have to worry too much with continuity as it could be a simple standalone "what if" series. Kinda like what Pretty Guardian Sailor Moon is to its anime and manga.
Toei already specializes in making monster and robot costumes for their various tokusatsu series that exist (i.e. - Super Sentai, Kamen Rider, Ultraman, the previous Metal Hero series, etc.), so I could see them making Decepticon Pretender shells, Autobot Pretender battle suits, Headmaster and Godmaster battle suits, and Autobot & Decepticon Robot Modes.
All the transformation sequences could be done similar to the transformations sequences of the various tokusatsu transforming mecha, and additional CGI could be used for things like laser blasts, Chōkon Power, and Devil Z himself.
Early episodes could use the Destroids as the Decepticon Pretenders' footsoldiers, but then get rid of them once the Headmaster Juniors are introduced (or maybe a little after).
It wouldn't necessarily need to follow the typical "Monster of the day gets destroyed each day"-style as the Decepticons would be used instead and wouldn't get destroyed till towards the end of the series (if they get destroyed at all, that is. As, none of the Cons, save for Devil Z/BlackZarak, got destroyed in the anime).
Also, most Japanese series of this kind tend to be better written and more mature than any American version, so don't just say "NO!" because of what the U.S. did to Super Sentai as Power Rangers.

(Also, I'm not sure if this does belong in this forum, or in another, so please move to the correct forum if needed)