We see here what Cybertron is like with the Functionists in control(operating from a giant Transformation cog and themselves Empurata'd, I suppose, to the point of making their decisions and actions logical and cold and to remove a more compassionate or emotional effect), and the issue almost beats you over the head with how their entire system is bent on What You Turn Into aka The Grand Cybertronian Taxonomy. They seek to become perfect; to find the perfect shape('Til All Are One?) and are essentially experimenting with the population to find it.
Megatron's speech in the previous issue(captured so delightfully well by Chris McFeely here on his Towards Peace bit:
http://www.SoundCloud.com/TheAudioKnightsTheatre - sorry, shameless plug) and the action of the rebel who threw her incendiary device fashioned from her own transformation cog(and why "females" in this continuity now? Did they never exodus because of the absence of war?) coupled by an "innocent" question posed by Roberts in the Twitter thread, seems to point to a theme of "Transformation Is Bad" - that this culture which exists with a natural ability to change into alternative forms is hindered by this very gift, in that they discriminate based on how this gift is used. We've seen Gorlam Prime and Beast Machines, of how evolution played a part in learning to change shape, but in a series ABOUT Transformers, it shines a light on what it really MEANS to be able to Transform.
The characters in "our" universe are comfortable in their alt modes; First Aid and Ambulon both led happy and fulfilling lives without needing to transform into something else - they found a use without needing transformation cogs.
When the Circle of Light left Cybertron to spread its message, when Nova Prime left to conquer, it seems the mechanical viewed the organic as inferior and it seems partly because of that inability to change shape.
I'm starting to ramble now, but I wonder what Roberts is building to, with this commentary on transformation. I Also need to read Eugenesis. It's on my list.
for Roberts being a big fan of the uk marvel stuff a homage of sorts to that series biggest arc isn't out of the question.
